Sven Bervoets - Postdoctoral Associate
I received my PhD in Biochemistry and Biotechnology at the University of Antwerp, Belgium, under the mentorship of Dr. Albena Jordanova. During this time, I studied the role of a cytoplasmic tRNA synthetase and its surprising nuclear role in Charcot-Marie-Tooth neuropathology. I used Drosophila melanogaster to show that both genetic and pharmacological exclusion of the mutant TyrRS protein prevents the disease phenotypes. Now, I pursue my postdoctoral research the Shepherd lab, where I focus on the role of dArc1 in memory and learning. I use Drosophila melanogaster to study such behaviours and the properties of the dArc1 protein in cell signalling.
Bervoets, S., Wei, N., Erfurth, M. et al. Transcriptional dysregulation by a nucleus-localized aminoacyl-tRNA synthetase associated with Charcot-Marie-Tooth neuropathy. Nat Commun 10, 5045 (2019) Read Article
Peeters, K., Bervoets, S. et al. Novel Mutations in the DYNC1H1 Tail Domain Refine the Genetic and Clinical Spectrum of Dyneinopathies. Hum Mutat 36(3), 287-91 (2015) Read Article