Radhika completed her bachelor’s in biotechnology at Jaypee Institute of Information Technology (India) and master’s in biomedical sciences at University College London (UK). She completed her PhD in neuroscience at University of Alabama at Birmingham in the lab of Dr. James H. Meador-Woodruff, where she investigated abnormalities in protein expression, protein complexes, phosphorylation, and kinase activity in the AKT-mTOR signaling cascade in postmortem human brain tissue from schizophrenia subjects, since this pathway plays an important role in learning and memory deficits observed in this mental illness. Now, as a postdoctoral associate, she is studying the role of Arc enriched EVs in Alzheimer’s disease using primary neurons and 3xTg mouse model.
Chadha R, Alganem K, Mccullumsmith RE and Meador-Woodruff JH. mTOR kinase activity regulates a phosphorylation signaling network in schizophrenia brain, Molecular Psychiatry, 2021, In press. Read Article
Mani S, Swargiary G and Chadha R. Mitophagy impairment in neurodegenerative diseases: pathogenesis and therapeutic interventions, Mitochondrion, 2021, In press. Read Article
Chadha R and Meador-Woodruff JH. Downregulated AKT-mTOR signaling pathway proteins in dorsolateral prefrontal cortex in Schizophrenia, Neuropsychopharmacology, 2020, 45:1059-1067. Read Article
Kapoor NK, Chadha R, Kumar S, Choedon T, Reddy VS, Kumar V. The HBx gene of hepatitis B virus can influence hepatic microenvironment via exosomes by transferring its mRNA and protein, Virus Research, 2017, 240:166-174. Read Article